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Relationship between Gene Body DNA Methylation and Intragenic H3K9me3 and H3K36me3 Chromatin Marks

To elucidate the relationship between intragenic DNA methylation and chromatin marks, we performed epigenetic profiling of chromosome 19 in human bronchial epithelial cells (HBEC) and in the colorectal cancer cell line HCT116 as well as its counterpart with double knockout of DNMT1 and DNMT3B (HCT11...

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Detalles Bibliográficos
Autores principales: Hahn, Maria A., Wu, Xiwei, Li, Arthur X., Hahn, Torsten, Pfeifer, Gerd P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079728/
https://www.ncbi.nlm.nih.gov/pubmed/21526191
http://dx.doi.org/10.1371/journal.pone.0018844