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Treatment of canine leukocyte adhesion deficiency by foamy virus vectors expressing CD18 from a PGK promoter

Proto-oncogene activation caused by retroviral vector integration can cause malignancies in gene therapy trials. This has led investigators to search for less genotoxic vectors with minimal enhancer activity and a decreased risk of influencing neighboring chromosomal gene expression after integratio...

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Detalles Bibliográficos
Autores principales:	Bauer, Thomas R, Olson, Erik M, Huo, Yunwen, Tuschong, Laura M, Allen, James M, Li, Yi, Burkholder, Tanya H, Russell, David W
Formato:	Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079787/ https://www.ncbi.nlm.nih.gov/pubmed/21228879 http://dx.doi.org/10.1038/gt.2010.169

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