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Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front–back polarity in migrating cells
Migratory front–back polarity emerges from the cooperative effect of myosin IIA (MIIA) and IIB (MIIB) on adhesive signaling. We demonstrate here that, during polarization, MIIA and MIIB coordinately promote localized actomyosin bundling, which generates large, stable adhesions that do not signal to...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080254/ https://www.ncbi.nlm.nih.gov/pubmed/21482721 http://dx.doi.org/10.1083/jcb.201012159 |