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Cdk2 loss accelerates precursor differentiation and remyelination in the adult central nervous system
The specific functions of intrinsic regulators of oligodendrocyte progenitor cell (OPC) division are poorly understood. Type 2 cyclin-dependent kinase (Cdk2) controls cell cycle progression of OPCs, but whether it acts during myelination and repair of demyelinating lesions remains unexplored. Here,...
Autores principales: | Caillava, Céline, Vandenbosch, Renaud, Jablonska, Beata, Deboux, Cyrille, Spigoni, Giulia, Gallo, Vittorio, Malgrange, Brigitte, Baron-Van Evercooren, Anne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080270/ https://www.ncbi.nlm.nih.gov/pubmed/21502361 http://dx.doi.org/10.1083/jcb.201004146 |
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