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Generation and Characterization of a genetic zebrafish model of SMA carrying the human SMN2 gene
BACKGROUND: Animal models of human diseases are essential as they allow analysis of the disease process at the cellular level and can advance therapeutics by serving as a tool for drug screening and target validation. Here we report the development of a complete genetic model of spinal muscular atro...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080329/ https://www.ncbi.nlm.nih.gov/pubmed/21443782 http://dx.doi.org/10.1186/1750-1326-6-24 |