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Continuous and low-energy (125)I seed irradiation changes DNA methyltransferases expression patterns and inhibits pancreatic cancer tumor growth

BACKGROUND: Iodine 125 ((125)I) seed irradiation is an effective treatment for unresectable pancreatic cancers. However, the radiobiological mechanisms underlying brachytherapy remain unclear. Therefore, we investigated the influence of continuous and low-energy (125)I irradiation on apoptosis, expr...

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Detalles Bibliográficos
Autores principales: Ma, Jian-xia, Jin, Zhen-dong, Si, Pei-ren, Liu, Yan, Lu, Zheng, Wu, Hong-yu, Pan, Xue, Wang, Luo-wei, Gong, Yan-fang, Gao, Jun, Zhao-shen, Li
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080330/
https://www.ncbi.nlm.nih.gov/pubmed/21457568
http://dx.doi.org/10.1186/1756-9966-30-35