Cargando…

Latexin expression is downregulated in human gastric carcinomas and exhibits tumor suppressor potential

BACKGROUND: Latexin, also known as endogenous carboxypeptidase inhibitor (CPI), has been found to inhibit mouse stem cell populations and lymphoma cell proliferation, demonstrating its potential role as a tumor suppressor. Our previous study also suggested a correlation between latexin expression an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yong, Basang, Zhuoma, Ding, Huirong, Lu, Zheming, Ning, Tao, Wei, Haoran, Cai, Hong, Ke, Yang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080345/ https://www.ncbi.nlm.nih.gov/pubmed/21466706 http://dx.doi.org/10.1186/1471-2407-11-121

Ejemplares similares

Latexin exhibits tumor-suppressor potential in pancreatic ductal adenocarcinoma
por: XUE, ZHANXIONG, et al.
Publicado: (2016)

The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy
por: Seed, Robert I., et al.
Publicado: (2019)

Self-assembly of human latexin into amyloid-like oligomers
por: Pallarés, Irantzu, et al.
Publicado: (2007)

The Hematopoietic Stem Cell Regulatory Gene Latexin has Tumor Suppressive Properties in Malignant Melanoma
por: Muthusamy, Viswanathan, et al.
Publicado: (2013)

Identification of latexin by a proteomic analysis in rat normal articular cartilage
por: Pérez, Elizabeth, et al.
Publicado: (2010)

Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance
por: Zhang, Cuiping, et al.
Publicado: (2020)

Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells
por: Xue, Zhan-Xiong, et al.
Publicado: (2014)

Latexin Is Down-Regulated in Hematopoietic Malignancies and Restoration of Expression Inhibits Lymphoma Growth
por: Liu, Yi, et al.
Publicado: (2012)

Clinical implications of AGBL2 expression and its inhibitor latexin in breast cancer
por: Zhang, Hao, et al.
Publicado: (2014)

DEC2 Serves as Potential Tumor Suppressor in Breast Carcinoma
por: Fang, Wentong, et al.
Publicado: (2020)

Nerve Injury Evoked Loss of Latexin Expression in Spinal Cord Neurons Contributes to the Development of Neuropathic Pain
por: Kühlein, Hilmar Nils, et al.
Publicado: (2011)

PAPP‐A functions as a tumor suppressor and is downregulated in renal cell carcinoma
por: Lu, Yanxin, et al.
Publicado: (2021)

Tumor suppressor miR-24 restrains gastric cancer progression by downregulating RegIV
por: Duan, Yantao, et al.
Publicado: (2014)

Downregulation of CD40 expression contributes to the accumulation of myeloid-derived suppressor cells in gastric tumors
por: SHEN, JIN, et al.
Publicado: (2014)

Downregulation of metastasis suppressor 1(MTSS1) is associated with nodal metastasis and poor outcome in Chinese patients with gastric cancer
por: Liu, Ke, et al.
Publicado: (2010)

LUCAT1 Epigenetically Downregulates the Tumor Suppressor Genes CXXC4 and SFRP2 in Gastric Cancer
por: Byun, Hyo Joo, et al.
Publicado: (2020)

Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice
por: Liu, Yi, et al.
Publicado: (2017)

Latexin deficiency attenuates adipocyte differentiation and protects mice against obesity and metabolic disorders induced by high-fat diet
por: Kan, Shuang, et al.
Publicado: (2022)

Latexin deletion protects against radiation-induced hematopoietic damages via selective activation of Bcl-2 prosurvival pathway
por: Zhang, Cuiping, et al.
Publicado: (2023)

Preliminary study on the inhibitory effect of tumor suppressor gene KPC1 on the proliferation in gastric carcinoma cell
por: Zhou, Min, et al.
Publicado: (2020)

REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype
por: Yu, J, et al.
Publicado: (2017)

Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway
por: You, Y, et al.
Publicado: (2014)

Proteomics reveals specific biological changes induced by the normothermic machine perfusion of donor kidneys with a significant up-regulation of Latexin
por: Zaza, Gianluigi, et al.
Publicado: (2023)

Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation
por: LIN, JIAYING, et al.
Publicado: (2014)

BDH2 is downregulated in hepatocellular carcinoma and acts as a tumor suppressor regulating cell apoptosis and autophagy
por: Liang, Hao, et al.
Publicado: (2019)

Kruppel-like factor 13 acts as a tumor suppressor in thyroid carcinoma by downregulating IFIT1
por: Liu, Yang, et al.
Publicado: (2023)

TNRC6C Functions as a Tumor Suppressor and Is Frequently Downregulated in Papillary Thyroid Cancer
por: Cai, Zhenqin, et al.
Publicado: (2021)

Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway
por: Li, Yaping, et al.
Publicado: (2020)

Latexin regulates sex dimorphism in hematopoiesis via gender-specific differential expression of microRNA 98-3p and thrombospondin 1
por: Cui, Xiaojing, et al.
Publicado: (2023)

Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma
por: Xiao, Ye, et al.
Publicado: (2020)

Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations
por: Aslan, Derya, et al.
Publicado: (2016)

Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma
por: Zhou, Jiahui, et al.
Publicado: (2016)

SH3BGRL2, a new downregulated tumor suppressor in clear cell renal cell carcinomas
por: Dufies, Maeva
Publicado: (2020)

WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression
por: Wu, Man, et al.
Publicado: (2021)

MiR-765 functions as a tumour suppressor and eliminates lipids in clear cell renal cell carcinoma by downregulating PLP2
por: Xiao, Wen, et al.
Publicado: (2020)

Eupafolin Exhibits Potent Anti-Angiogenic and Antitumor Activity in Hepatocellular Carcinoma
por: Jiang, Honglei, et al.
Publicado: (2017)

CHAC2, downregulated in gastric and colorectal cancers, acted as a tumor suppressor inducing apoptosis and autophagy through unfolded protein response
por: Liu, Shuiping, et al.
Publicado: (2017)

MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B
por: Chen, Xi, et al.
Publicado: (2022)

NOL4 is Downregulated and Hyper-Methylated in Papillary Thyroid Carcinoma Suggesting Its Role as a Tumor Suppressor Gene
por: Sheikholeslami, Sara, et al.
Publicado: (2020)

Circulating and Tumor-Infiltrating Myeloid-Derived Suppressor Cells in Patients with Colorectal Carcinoma
por: Zhang, Bin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_l6esvhsfbpo9pgkcp8rl68v2le