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Modeling the TNFα-Induced Apoptosis Pathway in Hepatocytes

The proinflammatory cytokine TNFα fails to provoke cell death in isolated hepatocytes but has been implicated in hepatocyte apoptosis during liver diseases associated with chronic inflammation. Recently, we showed that TNFα is able to sensitize primary murine hepatocytes cultured on collagen to Fas...

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Detalles Bibliográficos
Autores principales: Schlatter, Rebekka, Schmich, Kathrin, Lutz, Anna, Trefzger, Judith, Sawodny, Oliver, Ederer, Michael, Merfort, Irmgard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080376/
https://www.ncbi.nlm.nih.gov/pubmed/21533085
http://dx.doi.org/10.1371/journal.pone.0018646