Ubiquitin-Dependent Control of Class II MHC Localization Is Dispensable for Antigen Presentation and Antibody Production

Controlled localization of class II MHC molecules is essential for proper class II MHC-restricted antigen presentation and the subsequent initiation of an adaptive immune response. Ubiquitination of class II MHC molecules on cytosolic lysine (K225) of the β-chain has been shown to affect localizatio...

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Detalles Bibliográficos
Autores principales: McGehee, Annette M., Strijbis, Karin, Guillen, Eduardo, Eng, Thomas, Kirak, Oktay, Ploegh, Hidde L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080378/
https://www.ncbi.nlm.nih.gov/pubmed/21533087
http://dx.doi.org/10.1371/journal.pone.0018817

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