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Decreased Expression and Induced Nucleocytoplasmic Translocation of Pancreatic and Duodenal Homeobox 1 in INS-1 Cells Exposed to High Glucose and Palmitate

BACKGROUND: Type 2 diabetes mellitus (T2DM) is often accompanied by increased levels of circulating fatty acid. Elevations in fatty acids and glucose for prolonged periods of time have been suggested to cause progressive dysfunction or apoptosis of pancreatic beta cells in T2DM. However, the precise...

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Detalles Bibliográficos
Autores principales:	Ryu, Gyeong Ryul, Yoo, Jun Mo, Lee, Esder, Ko, Seung-Hyun, Ahn, Yu-Bae, Song, Ki-Ho
Formato:	Texto
Lenguaje:	English
Publicado:	Korean Diabetes Association 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080567/ https://www.ncbi.nlm.nih.gov/pubmed/21537415 http://dx.doi.org/10.4093/dmj.2011.35.1.65

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