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Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability

Surgical resection for colorectal liver metastases may only be considered when an adequate functional residual volume can be preserved. Selective portal venous embolisation may be used to increase this volume, whilst chemotherapy and radiofrequency ablation (RFA) can be used to treat inoperable lesi...

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Autores principales: Jones, R.T., French, J.J., Scott, J., Manas, D.M., Charnley, R.M.
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080585/
https://www.ncbi.nlm.nih.gov/pubmed/21512619
http://dx.doi.org/10.1159/000326959
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author Jones, R.T.
French, J.J.
Scott, J.
Manas, D.M.
Charnley, R.M.
author_facet Jones, R.T.
French, J.J.
Scott, J.
Manas, D.M.
Charnley, R.M.
author_sort Jones, R.T.
collection PubMed
description Surgical resection for colorectal liver metastases may only be considered when an adequate functional residual volume can be preserved. Selective portal venous embolisation may be used to increase this volume, whilst chemotherapy and radiofrequency ablation (RFA) can be used to treat inoperable lesions. A 73-year-old man with liver metastasis proceeded to surgery, with the intention to perform a right hemi-hepatectomy. Unexpectedly at laparotomy, despite adequate pre-operative imaging, both the right and middle hepatic veins were involved. At that time extended right hemi-hepatectomy was contraindicated by insufficient residual volume and RFA was performed. Follow-up imaging revealed atrophy of the lesion. Significantly, there was also left lateral lobe hypertrophy sufficient to permit resection, which was performed without complication. Thrombosis of intra-hepatic portal veins is a recognised complication of RFA but here it appears to have been beneficial. The case highlights the need for regular review of unresectable hepatic disease by a liver surgeon and could suggest new modalities of portal embolisation.
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spelling pubmed-30805852011-04-21 Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability Jones, R.T. French, J.J. Scott, J. Manas, D.M. Charnley, R.M. Case Rep Gastroenterol Published: April 2011 Surgical resection for colorectal liver metastases may only be considered when an adequate functional residual volume can be preserved. Selective portal venous embolisation may be used to increase this volume, whilst chemotherapy and radiofrequency ablation (RFA) can be used to treat inoperable lesions. A 73-year-old man with liver metastasis proceeded to surgery, with the intention to perform a right hemi-hepatectomy. Unexpectedly at laparotomy, despite adequate pre-operative imaging, both the right and middle hepatic veins were involved. At that time extended right hemi-hepatectomy was contraindicated by insufficient residual volume and RFA was performed. Follow-up imaging revealed atrophy of the lesion. Significantly, there was also left lateral lobe hypertrophy sufficient to permit resection, which was performed without complication. Thrombosis of intra-hepatic portal veins is a recognised complication of RFA but here it appears to have been beneficial. The case highlights the need for regular review of unresectable hepatic disease by a liver surgeon and could suggest new modalities of portal embolisation. S. Karger AG 2011-04-06 /pmc/articles/PMC3080585/ /pubmed/21512619 http://dx.doi.org/10.1159/000326959 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: April 2011
Jones, R.T.
French, J.J.
Scott, J.
Manas, D.M.
Charnley, R.M.
Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability
title Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability
title_full Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability
title_fullStr Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability
title_full_unstemmed Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability
title_short Radiofrequency Ablation Resulting in Left Lobe Hypertrophy and Improved Resectability
title_sort radiofrequency ablation resulting in left lobe hypertrophy and improved resectability
topic Published: April 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080585/
https://www.ncbi.nlm.nih.gov/pubmed/21512619
http://dx.doi.org/10.1159/000326959
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