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Gene Expression Profiling in Rodent Models for Schizophrenia
The complex neurodevelopmental disorder schizophrenia is thought to be induced by an interaction between predisposing genes and environmental stressors. In order to get a better insight into the aetiology of this complex disorder, animal models have been developed. In this review, we summarize mRNA...
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Formato: | Texto |
Lenguaje: | English |
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Bentham Science Publishers Ltd
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080594/ https://www.ncbi.nlm.nih.gov/pubmed/21629445 http://dx.doi.org/10.2174/157015910793358132 |
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author | Schijndel, Jessica E. Van Martens, Gerard J.M |
author_facet | Schijndel, Jessica E. Van Martens, Gerard J.M |
author_sort | Schijndel, Jessica E. Van |
collection | PubMed |
description | The complex neurodevelopmental disorder schizophrenia is thought to be induced by an interaction between predisposing genes and environmental stressors. In order to get a better insight into the aetiology of this complex disorder, animal models have been developed. In this review, we summarize mRNA expression profiling studies on neurodevelopmental, pharmacological and genetic animal models for schizophrenia. We discuss parallels and contradictions among these studies, and propose strategies for future research. |
format | Text |
id | pubmed-3080594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Bentham Science Publishers Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-30805942011-06-01 Gene Expression Profiling in Rodent Models for Schizophrenia Schijndel, Jessica E. Van Martens, Gerard J.M Curr Neuropharmacol Article The complex neurodevelopmental disorder schizophrenia is thought to be induced by an interaction between predisposing genes and environmental stressors. In order to get a better insight into the aetiology of this complex disorder, animal models have been developed. In this review, we summarize mRNA expression profiling studies on neurodevelopmental, pharmacological and genetic animal models for schizophrenia. We discuss parallels and contradictions among these studies, and propose strategies for future research. Bentham Science Publishers Ltd 2010-12 /pmc/articles/PMC3080594/ /pubmed/21629445 http://dx.doi.org/10.2174/157015910793358132 Text en ©2010 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Schijndel, Jessica E. Van Martens, Gerard J.M Gene Expression Profiling in Rodent Models for Schizophrenia |
title | Gene Expression Profiling in Rodent Models for Schizophrenia |
title_full | Gene Expression Profiling in Rodent Models for Schizophrenia |
title_fullStr | Gene Expression Profiling in Rodent Models for Schizophrenia |
title_full_unstemmed | Gene Expression Profiling in Rodent Models for Schizophrenia |
title_short | Gene Expression Profiling in Rodent Models for Schizophrenia |
title_sort | gene expression profiling in rodent models for schizophrenia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080594/ https://www.ncbi.nlm.nih.gov/pubmed/21629445 http://dx.doi.org/10.2174/157015910793358132 |
work_keys_str_mv | AT schijndeljessicaevan geneexpressionprofilinginrodentmodelsforschizophrenia AT martensgerardjm geneexpressionprofilinginrodentmodelsforschizophrenia |