Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV

Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by ICT (Immuno-chromatographic test), ELISA and...

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Autores principales: Khan, Najib U, Ali, Ijaz, Ahmad, Naeem U, Iqbal, Aqib, Rehman, Latif U, Munir, Iqbal, Rehman, Muti U, Khan, Sanaullah, Ali, Sajid, Siddique, Lubna, Swati, Zahoor A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080828/
https://www.ncbi.nlm.nih.gov/pubmed/21457531
http://dx.doi.org/10.1186/1743-422X-8-154
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author Khan, Najib U
Ali, Ijaz
Ahmad, Naeem U
Iqbal, Aqib
Rehman, Latif U
Munir, Iqbal
Rehman, Muti U
Khan, Sanaullah
Ali, Sajid
Siddique, Lubna
Swati, Zahoor A
author_facet Khan, Najib U
Ali, Ijaz
Ahmad, Naeem U
Iqbal, Aqib
Rehman, Latif U
Munir, Iqbal
Rehman, Muti U
Khan, Sanaullah
Ali, Sajid
Siddique, Lubna
Swati, Zahoor A
author_sort Khan, Najib U
collection PubMed
description Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by ICT (Immuno-chromatographic test), ELISA and RT-PCR. Out of the 7148 blood donors, 224 (3.13%) were positive for anti-HCV antibodies by ICT, 135 (1.89%) by ELISA while 118 (1.65%) blood donors had active HCV infection as detected by RT-PCR. We suggest that ELISA should be used for anti-HCV screening in public sector hospitals and health care units.
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spelling pubmed-30808282011-04-22 Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV Khan, Najib U Ali, Ijaz Ahmad, Naeem U Iqbal, Aqib Rehman, Latif U Munir, Iqbal Rehman, Muti U Khan, Sanaullah Ali, Sajid Siddique, Lubna Swati, Zahoor A Virol J Research Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by ICT (Immuno-chromatographic test), ELISA and RT-PCR. Out of the 7148 blood donors, 224 (3.13%) were positive for anti-HCV antibodies by ICT, 135 (1.89%) by ELISA while 118 (1.65%) blood donors had active HCV infection as detected by RT-PCR. We suggest that ELISA should be used for anti-HCV screening in public sector hospitals and health care units. BioMed Central 2011-04-01 /pmc/articles/PMC3080828/ /pubmed/21457531 http://dx.doi.org/10.1186/1743-422X-8-154 Text en Copyright ©2011 Khan et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Khan, Najib U
Ali, Ijaz
Ahmad, Naeem U
Iqbal, Aqib
Rehman, Latif U
Munir, Iqbal
Rehman, Muti U
Khan, Sanaullah
Ali, Sajid
Siddique, Lubna
Swati, Zahoor A
Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
title Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
title_full Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
title_fullStr Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
title_full_unstemmed Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
title_short Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
title_sort prevalence of active hcv infection among the blood donors of khyber pakhtunkwa and fata region of pakistan and evaluation of the screening tests for anti-hcv
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080828/
https://www.ncbi.nlm.nih.gov/pubmed/21457531
http://dx.doi.org/10.1186/1743-422X-8-154
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