Engineered Resistance to Plasmodium falciparum Development in Transgenic Anopheles stephensi

Transposon-mediated transformation was used to produce Anopheles stephensi that express single-chain antibodies (scFvs) designed to target the human malaria parasite, Plasmodium falciparum. The scFvs, m1C3, m4B7, and m2A10, are derived from mouse monoclonal antibodies that inhibit either ookinete in...

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Detalles Bibliográficos
Autores principales: Isaacs, Alison T., Li, Fengwu, Jasinskiene, Nijole, Chen, Xiaoguang, Nirmala, Xavier, Marinotti, Osvaldo, Vinetz, Joseph M., James, Anthony A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080844/
https://www.ncbi.nlm.nih.gov/pubmed/21533066
http://dx.doi.org/10.1371/journal.ppat.1002017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080844/
https://www.ncbi.nlm.nih.gov/pubmed/21533066
http://dx.doi.org/10.1371/journal.ppat.1002017

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