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Engineered Resistance to Plasmodium falciparum Development in Transgenic Anopheles stephensi

Transposon-mediated transformation was used to produce Anopheles stephensi that express single-chain antibodies (scFvs) designed to target the human malaria parasite, Plasmodium falciparum. The scFvs, m1C3, m4B7, and m2A10, are derived from mouse monoclonal antibodies that inhibit either ookinete in...

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Detalles Bibliográficos
Autores principales:	Isaacs, Alison T., Li, Fengwu, Jasinskiene, Nijole, Chen, Xiaoguang, Nirmala, Xavier, Marinotti, Osvaldo, Vinetz, Joseph M., James, Anthony A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080844/ https://www.ncbi.nlm.nih.gov/pubmed/21533066 http://dx.doi.org/10.1371/journal.ppat.1002017

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