Accessing a Hidden Conformation of the Maltose Binding Protein Using Accelerated Molecular Dynamics

Periplasmic binding proteins (PBPs) are a large family of molecular transporters that play a key role in nutrient uptake and chemotaxis in Gram-negative bacteria. All PBPs have characteristic two-domain architecture with a central interdomain ligand-binding cleft. Upon binding to their respective li...

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Detalles Bibliográficos
Autores principales: Bucher, Denis, Grant, Barry J., Markwick, Phineus R., McCammon, J. Andrew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080849/
https://www.ncbi.nlm.nih.gov/pubmed/21533070
http://dx.doi.org/10.1371/journal.pcbi.1002034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080849/
https://www.ncbi.nlm.nih.gov/pubmed/21533070
http://dx.doi.org/10.1371/journal.pcbi.1002034

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