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Accessing a Hidden Conformation of the Maltose Binding Protein Using Accelerated Molecular Dynamics
Periplasmic binding proteins (PBPs) are a large family of molecular transporters that play a key role in nutrient uptake and chemotaxis in Gram-negative bacteria. All PBPs have characteristic two-domain architecture with a central interdomain ligand-binding cleft. Upon binding to their respective li...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080849/ https://www.ncbi.nlm.nih.gov/pubmed/21533070 http://dx.doi.org/10.1371/journal.pcbi.1002034 |