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Linking Microscopic Spatial Patterns of Tissue Destruction in Emphysema to Macroscopic Decline in Stiffness Using a 3D Computational Model
Pulmonary emphysema is a connective tissue disease characterized by the progressive destruction of alveolar walls leading to airspace enlargement and decreased elastic recoil of the lung. However, the relationship between microscopic tissue structure and decline in stiffness of the lung is not well...
Autores principales: | Parameswaran, Harikrishnan, Majumdar, Arnab, Suki, Béla |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080851/ https://www.ncbi.nlm.nih.gov/pubmed/21533072 http://dx.doi.org/10.1371/journal.pcbi.1001125 |
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