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Respiratory Syncytial Virus Interferon Antagonist NS1 Protein Suppresses and Skews the Human T Lymphocyte Response
We recently demonstrated that the respiratory syncytial virus (RSV) NS1 protein, an antagonist of host type I interferon (IFN-I) production and signaling, has a suppressive effect on the maturation of human dendritic cells (DC) that was only partly dependent on released IFN-I. Here we investigated w...
Autores principales: | Munir, Shirin, Hillyer, Philippa, Le Nouën, Cyril, Buchholz, Ursula J., Rabin, Ronald L., Collins, Peter L., Bukreyev, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080852/ https://www.ncbi.nlm.nih.gov/pubmed/21533073 http://dx.doi.org/10.1371/journal.ppat.1001336 |
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