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GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma

Non-Hodgkin lymphoma (NHL) represents a diverse group of hematological malignancies, of which follicular lymphoma (FL) is a prevalent subtype. A previous genome-wide association study has established a marker, rs10484561 in the human leukocyte antigen (HLA) class II region on 6p21.32 associated with...

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Detalles Bibliográficos
Autores principales: Smedby, Karin E., Foo, Jia Nee, Skibola, Christine F., Darabi, Hatef, Conde, Lucia, Hjalgrim, Henrik, Kumar, Vikrant, Chang, Ellen T., Rothman, Nathaniel, Cerhan, James R., Brooks-Wilson, Angela R., Rehnberg, Emil, Irwan, Ishak D., Ryder, Lars P., Brown, Peter N., Bracci, Paige M., Agana, Luz, Riby, Jacques, Cozen, Wendy, Davis, Scott, Hartge, Patricia, Morton, Lindsay M., Severson, Richard K., Wang, Sophia S., Slager, Susan L., Fredericksen, Zachary S., Novak, Anne J., Kay, Neil E., Habermann, Thomas M., Armstrong, Bruce, Kricker, Anne, Milliken, Sam, Purdue, Mark P., Vajdic, Claire M., Boyle, Peter, Lan, Qing, Zahm, Shelia H., Zhang, Yawei, Zheng, Tongzhang, Leach, Stephen, Spinelli, John J., Smith, Martyn T., Chanock, Stephen J., Padyukov, Leonid, Alfredsson, Lars, Klareskog, Lars, Glimelius, Bengt, Melbye, Mads, Liu, Edison T., Adami, Hans-Olov, Humphreys, Keith, Liu, Jianjun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080853/
https://www.ncbi.nlm.nih.gov/pubmed/21533074
http://dx.doi.org/10.1371/journal.pgen.1001378