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Loss of ATF2 Function Leads to Cranial Motoneuron Degeneration during Embryonic Mouse Development

The AP-1 family transcription factor ATF2 is essential for development and tissue maintenance in mammals. In particular, ATF2 is highly expressed and activated in the brain and previous studies using mouse knockouts have confirmed its requirement in the cerebellum as well as in vestibular sense orga...

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Detalles Bibliográficos
Autores principales: Ackermann, Julien, Ashton, Garry, Lyons, Steve, James, Dominic, Hornung, Jean-Pierre, Jones, Nic, Breitwieser, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080913/
https://www.ncbi.nlm.nih.gov/pubmed/21533046
http://dx.doi.org/10.1371/journal.pone.0019090