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Loss of ATF2 Function Leads to Cranial Motoneuron Degeneration during Embryonic Mouse Development
The AP-1 family transcription factor ATF2 is essential for development and tissue maintenance in mammals. In particular, ATF2 is highly expressed and activated in the brain and previous studies using mouse knockouts have confirmed its requirement in the cerebellum as well as in vestibular sense orga...
Autores principales: | Ackermann, Julien, Ashton, Garry, Lyons, Steve, James, Dominic, Hornung, Jean-Pierre, Jones, Nic, Breitwieser, Wolfgang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080913/ https://www.ncbi.nlm.nih.gov/pubmed/21533046 http://dx.doi.org/10.1371/journal.pone.0019090 |
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