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p53 Hypersensitivity Is the Predominant Mechanism of the Unique Responsiveness of Testicular Germ Cell Tumor (TGCT) Cells to Cisplatin

Consistent with the excellent clinical results in testicular germ cell tumors (TGCT), most cell lines derived from this cancer show an exquisite sensitivity to Cisplatin. It is well accepted that the high susceptibility of TGCT cells to apoptosis plays a central role in this hypersensitive phenotype...

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Detalles Bibliográficos
Autores principales:	Gutekunst, Matthias, Oren, Moshe, Weilbacher, Andrea, Dengler, Michael A., Markwardt, Christiane, Thomale, Jürgen, Aulitzky, Walter E., van der Kuip, Heiko
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080918/ https://www.ncbi.nlm.nih.gov/pubmed/21532991 http://dx.doi.org/10.1371/journal.pone.0019198

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