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Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human Exposure

OBJECTIVE: Daily adult human exposure to bisphenol A (BPA) has been estimated at < 1 μg/kg, with virtually complete first-pass conjugation in the liver in primates but not in mice. We measured unconjugated and conjugated BPA levels in serum from adult female rhesus monkeys and adult female mice a...

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Detalles Bibliográficos
Autores principales: Taylor, Julia A., vom Saal, Frederick S., Welshons, Wade V., Drury, Bertram, Rottinghaus, George, Hunt, Patricia A., Toutain, Pierre-Louis, Laffont, Céline M., VandeVoort, Catherine A.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080921/
https://www.ncbi.nlm.nih.gov/pubmed/20855240
http://dx.doi.org/10.1289/ehp.1002514