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Dynamics of cancer cell subpopulations in primary and metastatic colorectal tumors
Intratumor heterogeneity—heterogeneity of cancer cells within a single tumor—is considered one of the most problematic factors of treatment. Genetic heterogeneity, such as in somatic mutations and chromosome aberrations, is a common characteristic of human solid tumors and is probably the basis of b...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081061/ https://www.ncbi.nlm.nih.gov/pubmed/21380628 http://dx.doi.org/10.1007/s10585-011-9381-0 |