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Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines
Gli1 is an established oncogene and its expression in Estrogen Receptor (ER) α negative and triple negative breast cancers is predictive of a poor prognosis; however, the biological functions regulated by Gli1 in breast cancer have not been extensively evaluated. Herein, Gli1 was over-expressed or d...
Autores principales: | Kwon, Yeon-Jin, Hurst, Douglas R., Steg, Adam D., Yuan, Kun, Vaidya, Kedar S., Welch, Danny R., Frost, Andra R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081062/ https://www.ncbi.nlm.nih.gov/pubmed/21442356 http://dx.doi.org/10.1007/s10585-011-9382-z |
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