Multidimensional Scaling Reveals the Main Evolutionary Pathways of Class A G-Protein-Coupled Receptors

Class A G-protein-coupled receptors (GPCRs) constitute the largest family of transmembrane receptors in the human genome. Understanding the mechanisms which drove the evolution of such a large family would help understand the specificity of each GPCR sub-family with applications to drug design. To g...

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Detalles Bibliográficos
Autores principales: Pelé, Julien, Abdi, Hervé, Moreau, Matthieu, Thybert, David, Chabbert, Marie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081337/
https://www.ncbi.nlm.nih.gov/pubmed/21544207
http://dx.doi.org/10.1371/journal.pone.0019094

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