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Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model

Our previous studies have found that activation of Wnt/β-Catenin signaling resulted in mouse prostatic intraepithelial neoplasia (mPIN). In the large probasin promoter directed SV40-Large T-antigen (LPB-Tag) expressing mouse prostate, mPIN forms with rare areas of adenocarcinoma. Combining expressio...

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Detalles Bibliográficos
Autores principales: Yu, Xiuping, Wang, Yongqing, DeGraff, David J., Wills, Marcia L., Matusik, Robert J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081383/
https://www.ncbi.nlm.nih.gov/pubmed/21151173
http://dx.doi.org/10.1038/onc.2010.560