Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus

OBJECTIVE: In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq. MATERIALS AND METHODS: The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant...

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Autores principales: Sousa, Erlanio O., Almeida, Thiago S., Rodrigues, Fabíola F.G., Campos, Adriana R., Lima, Sidney G., Costa, José G.M.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081458/
https://www.ncbi.nlm.nih.gov/pubmed/21572654
http://dx.doi.org/10.4103/0253-7613.77359
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author Sousa, Erlanio O.
Almeida, Thiago S.
Rodrigues, Fabíola F.G.
Campos, Adriana R.
Lima, Sidney G.
Costa, José G.M.
author_facet Sousa, Erlanio O.
Almeida, Thiago S.
Rodrigues, Fabíola F.G.
Campos, Adriana R.
Lima, Sidney G.
Costa, José G.M.
author_sort Sousa, Erlanio O.
collection PubMed
description OBJECTIVE: In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq. MATERIALS AND METHODS: The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of Escherichia coli (Ec 27) and Staphylococcus aureus (Sa 358) were used. RESULTS: The results show the inhibitory activity of LELm against E. coli (minimal inhibitory concentration [MIC] 16 μg/mL) and S. aureus (MIC 128 μg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against E. coli with MIC reduction (312 to 2 μL). CONCLUSION: The data from this study are indicative of the activity antibacterial of extracts of L. montevidensis and its potential in modifying the resistance of aminoglycosides.
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spelling pubmed-30814582011-05-13 Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus Sousa, Erlanio O. Almeida, Thiago S. Rodrigues, Fabíola F.G. Campos, Adriana R. Lima, Sidney G. Costa, José G.M. Indian J Pharmacol Research Article OBJECTIVE: In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq. MATERIALS AND METHODS: The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of Escherichia coli (Ec 27) and Staphylococcus aureus (Sa 358) were used. RESULTS: The results show the inhibitory activity of LELm against E. coli (minimal inhibitory concentration [MIC] 16 μg/mL) and S. aureus (MIC 128 μg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against E. coli with MIC reduction (312 to 2 μL). CONCLUSION: The data from this study are indicative of the activity antibacterial of extracts of L. montevidensis and its potential in modifying the resistance of aminoglycosides. Medknow Publications 2011-04 /pmc/articles/PMC3081458/ /pubmed/21572654 http://dx.doi.org/10.4103/0253-7613.77359 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sousa, Erlanio O.
Almeida, Thiago S.
Rodrigues, Fabíola F.G.
Campos, Adriana R.
Lima, Sidney G.
Costa, José G.M.
Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus
title Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus
title_full Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus
title_fullStr Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus
title_full_unstemmed Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus
title_short Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus
title_sort lantana montevidensis briq improves the aminoglycoside activity against multiresistant escherichia coli and staphylococcus aureus
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081458/
https://www.ncbi.nlm.nih.gov/pubmed/21572654
http://dx.doi.org/10.4103/0253-7613.77359
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