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Chronic phenytoin therapy-induced vecuronium resistance

This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.

Detalles Bibliográficos
Autores principales: Chowdhury, Lopamudra, Laha, Arpita, Chaudhuri, Tamonash, Chatterjee, Suparna
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081468/
https://www.ncbi.nlm.nih.gov/pubmed/21572664
http://dx.doi.org/10.4103/0253-7613.77378
Descripción
Sumario:This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.