Chronic phenytoin therapy-induced vecuronium resistance

This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.

Detalles Bibliográficos
Autores principales: Chowdhury, Lopamudra, Laha, Arpita, Chaudhuri, Tamonash, Chatterjee, Suparna
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081468/
https://www.ncbi.nlm.nih.gov/pubmed/21572664
http://dx.doi.org/10.4103/0253-7613.77378
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author Chowdhury, Lopamudra
Laha, Arpita
Chaudhuri, Tamonash
Chatterjee, Suparna
author_facet Chowdhury, Lopamudra
Laha, Arpita
Chaudhuri, Tamonash
Chatterjee, Suparna
author_sort Chowdhury, Lopamudra
collection PubMed
description This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance.
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spelling pubmed-30814682011-05-13 Chronic phenytoin therapy-induced vecuronium resistance Chowdhury, Lopamudra Laha, Arpita Chaudhuri, Tamonash Chatterjee, Suparna Indian J Pharmacol Drug Watch This case report highlights a clinically significant pharmacokinetic drug interaction between phenytoin, a widely used anticonvulsant and vecuronium, a non-depolarizing neuromuscular blocker which led to vecuronium resistance. Medknow Publications 2011-04 /pmc/articles/PMC3081468/ /pubmed/21572664 http://dx.doi.org/10.4103/0253-7613.77378 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Chowdhury, Lopamudra
Laha, Arpita
Chaudhuri, Tamonash
Chatterjee, Suparna
Chronic phenytoin therapy-induced vecuronium resistance
title Chronic phenytoin therapy-induced vecuronium resistance
title_full Chronic phenytoin therapy-induced vecuronium resistance
title_fullStr Chronic phenytoin therapy-induced vecuronium resistance
title_full_unstemmed Chronic phenytoin therapy-induced vecuronium resistance
title_short Chronic phenytoin therapy-induced vecuronium resistance
title_sort chronic phenytoin therapy-induced vecuronium resistance
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081468/
https://www.ncbi.nlm.nih.gov/pubmed/21572664
http://dx.doi.org/10.4103/0253-7613.77378
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AT lahaarpita chronicphenytointherapyinducedvecuroniumresistance
AT chaudhuritamonash chronicphenytointherapyinducedvecuroniumresistance
AT chatterjeesuparna chronicphenytointherapyinducedvecuroniumresistance

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