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Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA accumulation

PURPOSE: Ultraviolet B (UVB) irradiation activates nuclear factor-kappa B (NF-κB) and inducible nitric oxide synthase (iNOS) in the cornea, resulting in inflammatory responses and malondialdehyde (MDA) accumulation. This study aims to determine the effect of zerumbone, a potent NF-κB inhibitor and i...

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Detalles Bibliográficos
Autores principales: Chen, Bo-Yie, Lin, David Pei-Cheng, Wu, Chia-Yung, Teng, Mei-Ching, Sun, Chi-Yun, Tsai, Yuan-Ting, Su, Kuo-Chen, Wang, Soo-Ray, Chang, Han-Hsin
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081794/
https://www.ncbi.nlm.nih.gov/pubmed/21527993