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Functional analysis of disease-associated polymorphism LRP5.Q89R

PURPOSE: The canonical wingless and Int1 (Wnt) signaling pathway plays key roles in multiple biologic events. The pathway co-receptor, low density lipoprotein receptor-related protein 5 (LRP5), is involved in the pathogenesis of retinal diseases and has been implicated in glaucoma. We studied whethe...

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Detalles Bibliográficos
Autores principales: Mao, Weiming, Wordinger, Robert J., Clark, Abbot F.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081804/
https://www.ncbi.nlm.nih.gov/pubmed/21528003

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