Blockade of Persistent Sodium Currents Contributes to the Riluzole-Induced Inhibition of Spontaneous Activity and Oscillations in Injured DRG Neurons

In addition to a fast activating and immediately inactivating inward sodium current, many types of excitable cells possess a noninactivating or slowly inactivating component: the persistent sodium current (I(NaP)). The I(NaP) is found in normal primary sensory neurons where it is mediated by tetrodo...

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Detalles Bibliográficos
Autores principales: Xie, Rou-Gang, Zheng, Da-Wei, Xing, Jun-Ling, Zhang, Xu-Jie, Song, Ying, Xie, Ya-Bin, Kuang, Fang, Dong, Hui, You, Si-Wei, Xu, Hui, Hu, San-Jue
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081829/
https://www.ncbi.nlm.nih.gov/pubmed/21541342
http://dx.doi.org/10.1371/journal.pone.0018681

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