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SirT1 brings stemness closer to cancer and aging
Sirtuin 1 acts in various cell processes, deacetylating both chromatin and non-histone proteins, and its role in cancer and aging has long been studied and debated. Here we discuss another aspect of SirT1 biology, its function as a stem cell pluripotency and differentiation regulator. We evaluate th...
Autores principales: | Calvanese, Vincenzo, Fraga, Mario F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082011/ https://www.ncbi.nlm.nih.gov/pubmed/21307403 |
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