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Rosuvastatin Counteracts Vessel Arterialisation and Sinusoid Capillarisation, Reduces Tumour Growth, and Prolongs Survival in Murine Hepatocellular Carcinoma
Background and Aims. An arterial blood supply and phenotypic changes of the sinusoids characterise the liver vasculature in human hepatocellular carcinoma (HCC). We investigated the effects of rosuvastatin on liver vessel anomalies, tumour growth and survival in HCC. Methods. We treated transgenic m...
Autores principales: | Tijeras-Raballand, Annemilaï, Hainaud-Hakim, Patricia, Contreres, Jean-Olivier, Gest, Caroline, Le Henaff, Carole, Levy, Bernard I, Pocard, Marc, Soria, Claudine, Dupuy, Evelyne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082163/ https://www.ncbi.nlm.nih.gov/pubmed/21528105 http://dx.doi.org/10.1155/2010/640797 |
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