Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

How the Sec1/Munc18–syntaxin complex might transition to form the SNARE core complex remains unclear. Toward this, Munc18c tyrosine phosphorylation has been correlated with its dissociation from syntaxin 4. Using 3T3-L1 adipocytes subjected to small interfering ribonucleic acid reduction of Munc18c...

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Detalles Bibliográficos
Autores principales: Jewell, Jenna L., Oh, Eunjin, Ramalingam, Latha, Kalwat, Michael A., Tagliabracci, Vincent S., Tackett, Lixuan, Elmendorf, Jeffrey S., Thurmond, Debbie C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082181/
https://www.ncbi.nlm.nih.gov/pubmed/21444687
http://dx.doi.org/10.1083/jcb.201007176

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