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Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase

The unfolded protein response (UPR) activates Ire1, an endoplasmic reticulum (ER) resident transmembrane kinase and ribonuclease (RNase), in response to ER stress. We used an in vivo assay, in which disappearance of the UPR-induced spliced HAC1 messenger ribonucleic acid (mRNA) correlates with the r...

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Detalles Bibliográficos
Autores principales:	Chawla, Aditi, Chakrabarti, Sutapa, Ghosh, Gourisankar, Niwa, Maho
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082189/ https://www.ncbi.nlm.nih.gov/pubmed/21444691 http://dx.doi.org/10.1083/jcb.201008071

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