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Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b
A 78-year-old male who experienced multiple recurrences of hepatocellular carcinoma (HCC) with hepatitis C virus (HCV)-related cirrhosis underwent transcatheter arterial chemoembolization and ablation and survived for more than 10 years. His serum HCV RNA level was 2.8 log IU/ml and the serotype of...
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Formato: | Texto |
Lenguaje: | English |
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S. Karger AG
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082480/ https://www.ncbi.nlm.nih.gov/pubmed/21537363 http://dx.doi.org/10.1159/000323692 |
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author | Mamori, Satoshi Mamori, Hiroshi |
author_facet | Mamori, Satoshi Mamori, Hiroshi |
author_sort | Mamori, Satoshi |
collection | PubMed |
description | A 78-year-old male who experienced multiple recurrences of hepatocellular carcinoma (HCC) with hepatitis C virus (HCV)-related cirrhosis underwent transcatheter arterial chemoembolization and ablation and survived for more than 10 years. His serum HCV RNA level was 2.8 log IU/ml and the serotype of HCV was 2. He underwent long-term super-low-dose (20 μg/week) pegylated interferon-alpha 2b therapy to prevent recurrence of HCC. He became negative for HCV RNA 2 months later, and thereafter remained negative after the discontinuation of interferon therapy, and has not experienced a recurrence of HCC for more than 20 months. |
format | Text |
id | pubmed-3082480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-30824802011-05-02 Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b Mamori, Satoshi Mamori, Hiroshi Case Rep Gastroenterol Published: January 2011 A 78-year-old male who experienced multiple recurrences of hepatocellular carcinoma (HCC) with hepatitis C virus (HCV)-related cirrhosis underwent transcatheter arterial chemoembolization and ablation and survived for more than 10 years. His serum HCV RNA level was 2.8 log IU/ml and the serotype of HCV was 2. He underwent long-term super-low-dose (20 μg/week) pegylated interferon-alpha 2b therapy to prevent recurrence of HCC. He became negative for HCV RNA 2 months later, and thereafter remained negative after the discontinuation of interferon therapy, and has not experienced a recurrence of HCC for more than 20 months. S. Karger AG 2011-01-19 /pmc/articles/PMC3082480/ /pubmed/21537363 http://dx.doi.org/10.1159/000323692 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published: January 2011 Mamori, Satoshi Mamori, Hiroshi Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b |
title | Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b |
title_full | Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b |
title_fullStr | Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b |
title_full_unstemmed | Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b |
title_short | Hepatitis C-Related Cirrhosis with Sustained Prevention of Hepatocellular Carcinoma Recurrence by Long-Term Administration of Super-Low-Dose Peginterferon-Alpha 2b |
title_sort | hepatitis c-related cirrhosis with sustained prevention of hepatocellular carcinoma recurrence by long-term administration of super-low-dose peginterferon-alpha 2b |
topic | Published: January 2011 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082480/ https://www.ncbi.nlm.nih.gov/pubmed/21537363 http://dx.doi.org/10.1159/000323692 |
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