Neurosteroid Dehydroepiandrosterone Interacts with Nerve Growth Factor (NGF) Receptors, Preventing Neuronal Apoptosis

The neurosteroid dehydroepiandrosterone (DHEA), produced by neurons and glia, affects multiple processes in the brain, including neuronal survival and neurogenesis during development and in aging. We provide evidence that DHEA interacts with pro-survival TrkA and pro-death p75(NTR) membrane receptor...

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Detalles Bibliográficos
Autores principales: Lazaridis, Iakovos, Charalampopoulos, Ioannis, Alexaki, Vassilia-Ismini, Avlonitis, Nicolaos, Pediaditakis, Iosif, Efstathopoulos, Paschalis, Calogeropoulou, Theodora, Castanas, Elias, Gravanis, Achille
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082517/
https://www.ncbi.nlm.nih.gov/pubmed/21541365
http://dx.doi.org/10.1371/journal.pbio.1001051

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