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Alpha-Tomatine Induces Apoptosis and Inhibits Nuclear Factor-Kappa B Activation on Human Prostatic Adenocarcinoma PC-3 Cells

BACKGROUND: Alpha-tomatine (α-tomatine) is the major saponin in tomato (Lycopersicon esculentum). This study investigates the chemopreventive potential of α-tomatine on androgen-independent human prostatic adenocarcinoma PC-3 cells. METHODOLOGY/PRINCIPAL FINDINGS: Treatment of highly aggressive huma...

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Detalles Bibliográficos
Autores principales: Lee, Sui-Ting, Wong, Pooi-Fong, Cheah, Shiau-Chuen, Mustafa, Mohd Rais
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082542/
https://www.ncbi.nlm.nih.gov/pubmed/21541327
http://dx.doi.org/10.1371/journal.pone.0018915