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Wnt4 Enhances Murine Hematopoietic Progenitor Cell Expansion Through a Planar Cell Polarity-Like Pathway

BACKGROUND: While the role of canonical (β-catenin-mediated) Wnt signaling in hematolymphopoiesis has been studied extensively, little is known of the potential importance of non-canonical Wnt signals in hematopoietic cells. Wnt4 is one of the Wnt proteins that can elicit non-canonical pathways. We...

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Detalles Bibliográficos
Autores principales: Heinonen, Krista M., Vanegas, Juan Ruiz, Lew, Deborah, Krosl, Jana, Perreault, Claude
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082562/
https://www.ncbi.nlm.nih.gov/pubmed/21541287
http://dx.doi.org/10.1371/journal.pone.0019279