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Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line

BACKGROUND: Src and signaling molecules downstream of Src, including signal transducer and activator of transcription 3 (Stat3) and cMyc, have been implicated in the development, maintenance and/or progression of several types of human cancers, including breast cancer. Here we report the ability of...

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Detalles Bibliográficos
Autores principales: Bjorge, Jeffrey D., Pang, Andy S., Funnell, Melanie, Chen, Ke Yun, Diaz, Roman, Magliocco, Anthony M., Fujita, Donald J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082570/
https://www.ncbi.nlm.nih.gov/pubmed/21541295
http://dx.doi.org/10.1371/journal.pone.0019309