Endpoints in pediatric pain studies

Assessing pain intensity in (preverbal) children is more difficult than in adults. Tools to measure pain are being used as primary endpoints [e.g., pain intensity, time to first (rescue) analgesia, total analgesic consumption, adverse effects, and long-term effects] in studies on the effects of anal...

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Detalles Bibliográficos
Autores principales: van Dijk, Monique, Ceelie, Ilse, Tibboel, Dick
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082693/
https://www.ncbi.nlm.nih.gov/pubmed/21107829
http://dx.doi.org/10.1007/s00228-010-0947-6
Descripción
Sumario:Assessing pain intensity in (preverbal) children is more difficult than in adults. Tools to measure pain are being used as primary endpoints [e.g., pain intensity, time to first (rescue) analgesia, total analgesic consumption, adverse effects, and long-term effects] in studies on the effects of analgesic drugs. Here, we review current and promising new endpoints used in pediatric pain assessment studies.

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