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Endpoints in pediatric pain studies

Assessing pain intensity in (preverbal) children is more difficult than in adults. Tools to measure pain are being used as primary endpoints [e.g., pain intensity, time to first (rescue) analgesia, total analgesic consumption, adverse effects, and long-term effects] in studies on the effects of anal...

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Detalles Bibliográficos
Autores principales: van Dijk, Monique, Ceelie, Ilse, Tibboel, Dick
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082693/
https://www.ncbi.nlm.nih.gov/pubmed/21107829
http://dx.doi.org/10.1007/s00228-010-0947-6
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author van Dijk, Monique
Ceelie, Ilse
Tibboel, Dick
author_facet van Dijk, Monique
Ceelie, Ilse
Tibboel, Dick
author_sort van Dijk, Monique
collection PubMed
description Assessing pain intensity in (preverbal) children is more difficult than in adults. Tools to measure pain are being used as primary endpoints [e.g., pain intensity, time to first (rescue) analgesia, total analgesic consumption, adverse effects, and long-term effects] in studies on the effects of analgesic drugs. Here, we review current and promising new endpoints used in pediatric pain assessment studies.
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spelling pubmed-30826932011-06-06 Endpoints in pediatric pain studies van Dijk, Monique Ceelie, Ilse Tibboel, Dick Eur J Clin Pharmacol Review Article Assessing pain intensity in (preverbal) children is more difficult than in adults. Tools to measure pain are being used as primary endpoints [e.g., pain intensity, time to first (rescue) analgesia, total analgesic consumption, adverse effects, and long-term effects] in studies on the effects of analgesic drugs. Here, we review current and promising new endpoints used in pediatric pain assessment studies. Springer-Verlag 2010-11-24 2011 /pmc/articles/PMC3082693/ /pubmed/21107829 http://dx.doi.org/10.1007/s00228-010-0947-6 Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Review Article
van Dijk, Monique
Ceelie, Ilse
Tibboel, Dick
Endpoints in pediatric pain studies
title Endpoints in pediatric pain studies
title_full Endpoints in pediatric pain studies
title_fullStr Endpoints in pediatric pain studies
title_full_unstemmed Endpoints in pediatric pain studies
title_short Endpoints in pediatric pain studies
title_sort endpoints in pediatric pain studies
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082693/
https://www.ncbi.nlm.nih.gov/pubmed/21107829
http://dx.doi.org/10.1007/s00228-010-0947-6
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