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EPR Study of Iron Ion Complexes in Human Blood
Electronic states of iron ion complexes in human blood from patients with melanoma have been investigated by electron paramagnetic resonance (EPR). The measurements were performed at liquid nitrogen temperature (77 K) on an X-band EPR spectrometer. Numerous types of iron paramagnetic centers have be...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082697/ https://www.ncbi.nlm.nih.gov/pubmed/21654899 http://dx.doi.org/10.1007/s00723-011-0219-3 |
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author | Krzyminiewski, Ryszard Kruczyński, Zdzisław Dobosz, Bernadeta Zając, Anna Mackiewicz, Andrzej Leporowska, Ewa Folwaczna, Sandra |
author_facet | Krzyminiewski, Ryszard Kruczyński, Zdzisław Dobosz, Bernadeta Zając, Anna Mackiewicz, Andrzej Leporowska, Ewa Folwaczna, Sandra |
author_sort | Krzyminiewski, Ryszard |
collection | PubMed |
description | Electronic states of iron ion complexes in human blood from patients with melanoma have been investigated by electron paramagnetic resonance (EPR). The measurements were performed at liquid nitrogen temperature (77 K) on an X-band EPR spectrometer. Numerous types of iron paramagnetic centers have been identified. In several kinds of protein complexes exemplified by methemoglobin, transferrin or ferritin, various forms of trivalent iron have been found. Three groups of patients with typical EPR spectra have been individualized. These groups differed in types and concentration of paramagnetic centers in peripheral blood. A good correlation has been found between the EPR results, the total iron ion complexes concentration and transferrin saturation. |
format | Text |
id | pubmed-3082697 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-30826972011-06-06 EPR Study of Iron Ion Complexes in Human Blood Krzyminiewski, Ryszard Kruczyński, Zdzisław Dobosz, Bernadeta Zając, Anna Mackiewicz, Andrzej Leporowska, Ewa Folwaczna, Sandra Appl Magn Reson Article Electronic states of iron ion complexes in human blood from patients with melanoma have been investigated by electron paramagnetic resonance (EPR). The measurements were performed at liquid nitrogen temperature (77 K) on an X-band EPR spectrometer. Numerous types of iron paramagnetic centers have been identified. In several kinds of protein complexes exemplified by methemoglobin, transferrin or ferritin, various forms of trivalent iron have been found. Three groups of patients with typical EPR spectra have been individualized. These groups differed in types and concentration of paramagnetic centers in peripheral blood. A good correlation has been found between the EPR results, the total iron ion complexes concentration and transferrin saturation. Springer Vienna 2011-04-05 2011 /pmc/articles/PMC3082697/ /pubmed/21654899 http://dx.doi.org/10.1007/s00723-011-0219-3 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Article Krzyminiewski, Ryszard Kruczyński, Zdzisław Dobosz, Bernadeta Zając, Anna Mackiewicz, Andrzej Leporowska, Ewa Folwaczna, Sandra EPR Study of Iron Ion Complexes in Human Blood |
title | EPR Study of Iron Ion Complexes in Human Blood |
title_full | EPR Study of Iron Ion Complexes in Human Blood |
title_fullStr | EPR Study of Iron Ion Complexes in Human Blood |
title_full_unstemmed | EPR Study of Iron Ion Complexes in Human Blood |
title_short | EPR Study of Iron Ion Complexes in Human Blood |
title_sort | epr study of iron ion complexes in human blood |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082697/ https://www.ncbi.nlm.nih.gov/pubmed/21654899 http://dx.doi.org/10.1007/s00723-011-0219-3 |
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