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Soft tissue augmentation by autologous cultured fibroblasts transplantation for treatment of wrinkles and scars: a case series of 20 patients

BACKGROUND: There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, bio-synthetic, cadaver, animal and human sources. METHODS: The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fib...

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Detalles Bibliográficos
Autores principales: Nilforoushzadeh, Mohammad Ali, Siadat, Amir Hossein, Arianrad, Mojgan, Moulavi, Fariba, Baradaran, Elahe Haft, Esfahani, Mohhamad Hossein Nasr
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082806/
https://www.ncbi.nlm.nih.gov/pubmed/21526076
Descripción
Sumario:BACKGROUND: There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, bio-synthetic, cadaver, animal and human sources. METHODS: The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry. RESULTS: The mean of improvement for this procedure at the 6 month follow up was 41%. CONCLUSIONS: In conclusion autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars.