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Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats

BACKGROUND: The present study evaluated the effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats. METHODS: After 12 weeks of diabetes induction and exercise period, extracellular levels of glutamate and GABA were in...

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Autores principales: Reisi, Parham, Alaei, Hojjatallah, Babri, Shirin, Sharifi, Mohammad Reza, Mohaddes, Gisue, Soleimannejad, Elaheh, Rashidi, Bahman
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082807/
https://www.ncbi.nlm.nih.gov/pubmed/21526077
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author Reisi, Parham
Alaei, Hojjatallah
Babri, Shirin
Sharifi, Mohammad Reza
Mohaddes, Gisue
Soleimannejad, Elaheh
Rashidi, Bahman
author_facet Reisi, Parham
Alaei, Hojjatallah
Babri, Shirin
Sharifi, Mohammad Reza
Mohaddes, Gisue
Soleimannejad, Elaheh
Rashidi, Bahman
author_sort Reisi, Parham
collection PubMed
description BACKGROUND: The present study evaluated the effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats. METHODS: After 12 weeks of diabetes induction and exercise period, extracellular levels of glutamate and GABA were investigated. RESULTS: The results showed that glutamate levels were significantly decreased in diabetes-rest group comparing to the control-rest and the diabetes-exercise groups. CONCLUSIONS: The findings support the possibility that treadmill running is helpful in alleviating neurotransmitter homeostasis and alterations in transmission in diabetes mellitus.
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spelling pubmed-30828072011-04-27 Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats Reisi, Parham Alaei, Hojjatallah Babri, Shirin Sharifi, Mohammad Reza Mohaddes, Gisue Soleimannejad, Elaheh Rashidi, Bahman J Res Med Sci Short Communication BACKGROUND: The present study evaluated the effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats. METHODS: After 12 weeks of diabetes induction and exercise period, extracellular levels of glutamate and GABA were investigated. RESULTS: The results showed that glutamate levels were significantly decreased in diabetes-rest group comparing to the control-rest and the diabetes-exercise groups. CONCLUSIONS: The findings support the possibility that treadmill running is helpful in alleviating neurotransmitter homeostasis and alterations in transmission in diabetes mellitus. Medknow Publications 2010 /pmc/articles/PMC3082807/ /pubmed/21526077 Text en © Journal of Research in Medical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Reisi, Parham
Alaei, Hojjatallah
Babri, Shirin
Sharifi, Mohammad Reza
Mohaddes, Gisue
Soleimannejad, Elaheh
Rashidi, Bahman
Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats
title Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats
title_full Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats
title_fullStr Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats
title_full_unstemmed Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats
title_short Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats
title_sort effects of treadmill running on extracellular basal levels of glutamate and gaba at dentate gyrus of streptozotocin-induced diabetic rats
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082807/
https://www.ncbi.nlm.nih.gov/pubmed/21526077
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