Cargando…
Interaction of STAT6 with its co-activator SRC-1/NCoA-1 is regulated by dephosphorylation of the latter via PP2A
Regulation of gene expression represents a central issue in signal-regulated cellular responses. STAT6 is a critical mediator of IL-4 stimulated gene activation. To mediate this function, STAT6 recruits co-activator complexes. We have previously shown that STAT6 binds the PAS-B domain of the co-acti...
Autores principales: | Münz, Tobias, Litterst, Claudia M., Pfitzner, Edith |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082895/ https://www.ncbi.nlm.nih.gov/pubmed/21148148 http://dx.doi.org/10.1093/nar/gkq1225 |
Ejemplares similares
-
p160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain
por: Lodrini, Marco, et al.
Publicado: (2008) -
Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6
por: Russo, Luigi, et al.
Publicado: (2017) -
NCoA3 upregulation in breast cancer‑associated adipocytes elicits an inflammatory profile
por: Lira, María Cecilia, et al.
Publicado: (2023) -
Insights into the function of HDAC3 and NCoR1/NCoR2 co-repressor complex in metabolic diseases
por: Paluvai, Harikrishnareddy, et al.
Publicado: (2023) -
Nuclear receptor coactivator 6 (NCoA6) promotes cell proliferation, migration, and invasion in pancreatic cancer
por: Wang, Xin, et al.
Publicado: (2023)