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Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation(†)

Nucleoside Monophosphate Kinases (NMPKs) family are key enzymes in nucleotide metabolism. Bacterial UMPKs depart from the main superfamily of NMPKs. Having no eukaryotic counterparts they represent attractive therapeutic targets. They are regulated by GTP and UTP, while showing different mechanisms...

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Detalles Bibliográficos
Autores principales:	Labesse, Gilles, Benkali, Khaled, Salard-Arnaud, Isabelle, Gilles, Anne-Marie, Munier-Lehmann, Hélène
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082897/ https://www.ncbi.nlm.nih.gov/pubmed/21149268 http://dx.doi.org/10.1093/nar/gkq1250

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